Fall 2002                                     CARES Foundation, Inc.
Back to Fall 2002 Index

Home

CAH Research at Cornell

Dr. Maria I. New, Weill Medical College of Cornell University

   
Under the longest running grant issued by the National Institutes of Health, which was recently given a MERIT award (Mechanism to Extend Research in Time), Dr. Maria I. New is pursuing the following investigations related to congenital adrenal hyperplasia (CAH):

Prenatal diagnosis and treatment: Dr. New is compiling a complete library of the mutations in the 21-hydroxylase and 11 β-hydroxylase genes which cause classic (severe) and nonclassic (mild, late-onset) CAH. She has the only center in the United States which routinely provides prenatal diagnosis and treatment of classically affected female fetuses. Prenatal treatment with dexamethasone to the mother spares classically affected females genital ambiguity and the need for corrective surgery.

Improving final height of children with classic CAH: The combined drug regimen of leuprolide, which suppresses the onset of puberty, plus growth hormone has been shown to be effective in maximizing final height.

Fertility in CAH: Dr. New continues to investigate the factors that contribute to infertility in males and females with CAH.

Psychobiology of CAH: With her colleague Dr. Heino Meyer-Bahlburg, Dr. New is investigating the role of prenatal androgens in gender identity.

Treatment of nonclassic CAH: With one of the largest patient populations of nonclassic CAH in the world, Dr. New continues to refine treatment for the extremely variable symptoms of nonclassic CAH.

 

  
   

Back to Fall 2002 Index

Top

 Home
© 2002 CARES Foundation, Inc. All rights reserved. Republication or redistribution of CARES content, including by framing or similar means, is prohibited without the prior written consent of CARES.